
Release time:2022-09-24 Click:
Vitamin K2 (MK-7) is a type of vitamin K2, that is, seven isoprene units on the side chain of vitamin K2. It is a fat-soluble vitamin and one of the indispensable vitamins in the human body. It is also known as MK-7, menadione-7 and vitamin K2(35).
CAS NO.: 2124-57-4
Molecular formula: C46H64O2
Molecular weight: 649.00
Benefit
Vitamin K is an essential substance for the synthesis of four coagulation proteins (Prothrombin, Transformation accelerating factor, Anti hemophilia factor and Situ factor) in the liver, it plays an auxiliary role in the synthesis of γ- carboxyl glutamic acid. Vitamin K2, as a coenzyme of Glutamic acid- γ- Carboxylase, can carboxylate the glutamate residue on osteocalcin into Gla. After carboxylation, osteocalcin is activated. Gla binds and deposits with hydroxyapatite calcium to promote bone mineralization. If lacking of vitamin K2 in the body, it will lead to incomplete carboxylation of osteocalcin and the formation of undercarboxylated Osteocalcin (ucOC). The glutamic acid residues with incomplete carboxylation will affffect the mineralization of bone.
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