Release time：2025-10-31 Click:
1.Chemical Structure and Identity
IUPAC name: 4,5-Dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid disodium
Product Name: Pyrroloquinoline quinone disodium Salt
Chemical formula: C₁₄H₄N₂Na₂O₈
CAS Number: 122628-50-6
Molar mass: 374.17 g/mol
storage temp: 2-8℃
Form: Solid
Color: Pink to red
Water Solubility: 6.16mg/ml(in water)
Boiling point: 1018.6℃ at 760 mmHg
Flash point: 569.8℃
Steam pressure: 0mmHg at 25℃
2. Physical Appearance
PQQ disodium salt typically presents as a fine, free-flowing crystalline powder. Its color is a distinctive deep reddish-brown to burgundy, which is a characteristic visual identifier for the compound.
3. Solubility
A defining property of PQQ disodium salt is its high solubility in water. This is a direct result of its ionic salt form and the polar carboxylate groups, which readily form hydrogen bonds with water molecules. It is reported to have a solubility of >5000m g/L in aqueous solutions, forming a clear, deep red-colored solution.
Conversely, it has very low solubility in most organic solvents such as ethanol, methanol, acetone, ethyl acetate, and chloroform. This property is often exploited in purification processes.
4. Stability
Thermal Stability: PQQ disodium salt is relatively stable at room temperature when stored appropriately. It can withstand moderate heat, but decomposition will occur at elevated temperatures.
pH Stability: The stability of PQQ is highly pH-dependent. It is most stable in neutral to slightly basic conditions. Under strong acidic conditions, it can undergo degradation. The vibrant red color of its solution may also change with pH, often becoming lighter or yellowish in highly acidic environments.
Light Sensitivity: The compound is photosensitive. Exposure to direct light, especially ultraviolet (UV) light, can catalyze its decomposition. Therefore, it must be protected from light by storing it in amber glass containers or opaque packaging.
5. Spectroscopic Properties
The unique structure of PQQ disodium salt confers specific spectroscopic features that are vital for its identification and quantification.
UV-Vis Spectroscopy: In aqueous solution, PQQ disodium salt exhibits a strong absorbance in the ultraviolet and visible range. Its characteristic spectrum typically shows two major absorption peaks: one around 249 nm and a broader peak in the 330-340 nm region, which is responsible for its red color. The exact λmax can shift slightly depending on the solvent and pH.
Fluorescence: PQQ is intrinsically fluorescent. Its excitation maximum is around 360 nm, and it emits light with a maximum around 460 nm (blue-green emission). This fluorescence property is widely used in analytical methods like HPLC with fluorescence detection for highly sensitive and specific measurement.
6. Redox (Reduction-Oxidation) Properties
In living organisms, PQQ Powder exists in three forms based on its binding with electrons and hydrogen ions: the quinone form (PQQ), the semiquinone form (PQQH), and the hydroquinone form (PQQH2). These forms can interconvert through electron and proton transfer. The unique molecular structure of PQQ endows it with a high redox potential and combines the physicochemical properties of vitamin C, riboflavin, and pyridoxal. The stability and high redox potential of PQQ ensure its efficient electron transfer capability, enabling it to catalyze thousands of redox cycles in a single reaction. This makes PQQ the coenzyme with the highest known catalytic efficiency.
7. Hygroscopicity
PQQ disodium salt is moderately hygroscopic, meaning it can absorb moisture from the atmosphere if left exposed. This can lead to clumping or caking of the powder and may potentially impact its long-term stability. It is recommended to store it in a sealed container in a cool, dry place, often with desiccants.
→Email: info@leadingchemical.com←
More detail:https://www.leadingchemical.com/gb2312/PQQ/
Leadingchemical the Professional PQQ disodium supplier in China