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PQQ or methoxatin is now considered a vitamin-like compound and has been suggested to be a new member of the vitamin B-complex. Pyrroloquinoline quinone disodium salt contributes to cellular health and mitochondrial function, is beneficial to neuronal survival and memory, exhibits free-radical scavenging activity, and may be a vitamin-like factor essential for growth and reproduction in mammals and humans, as a dietary component in many foods.
It is believed that PQQ disodium salt is important for human health (Stites, 2000) based on the fact that animal diets deficient in PQQ led to poor growth, low energy, and aborted reproduction. Other signs of deficiency found in the purposely depleted diets were friable skin, hemorrhage, diverticulitis, lowered overall fitness, diminished fertility, and impaired immunity (Steinberg, 2003). The severely affected mice had connective tissue functional abnormalities, a reduction in the collagen crosslinking enzyme lysyl oxidase, and diminished skin collagen (Kumazawa, 1995). When PQQ is supplemented to a synthetic-nutrient-based diet, it enhances growth-related parameters in young mice.
In a L/RTP discussion twopage, Pyrroloquinoline quinone disodium salt is a crucial natural bioactive compound with multi-physiological activities. Firstly, PQQ disodium salt, as a natural antioxidant, can be applied in the field of food, pharmaceutical and cosmetics with the functions of antioxidation, anti-aging and beautifying. Second, PQQ disodium salt can also be used in the biofuel field, so as to enhance the combustion efficiency and the environmental protection property of the biofuel. Furthermore PQQ disodium salt is also applicable in the medical industry include cancer, cardiovascular and neural disorders. Finally, PQQ supplement is also employed in the realm of biology such as the investigation of cellular signal transduction and gene expression.
A placebo-controlled double-blind parallel group study was conducted to evaluate the effects of PQQ on memory and other cognitive function parameters in forgetful subjects aged 50 to 70 years. Subjects were administered PQQ alone, PQQ Powder in combination with CoQ10, or placebo for 24 weeks (Koikeda, 2011). They were assessed with a neuropsychological status screening test. The researchers reported that PQQ, either alone or in combination with CoQ10, may be capable of preventing or even reversing cognitive impairment. pqq vitamin enhanced not only the short-term memory but also other advanced cerebral functions including spatial recognition.
Seventeen adult human subjects (male and female) took part in a randomized, double-blind, placebo-controlled clinical study to examine the impact of 20 mg of PQQ on stress, fatigue, quality of life, and sleep. They took 20 milligrams of PQQ a day for 8 weeks. All of the six scales of vigor, fatigue, tension-anxiety, depression, anger-hostility and confusion were largely ameliorated after the administration of PQQ as compared to before. Quality of life, appetite, sleep, obsession, and pain also exhibited statistically significant improvements. A significant improvement in sleepiness at awakening, sleep onset and maintenance, and sleep duration also occurred. These changes in the global scores were correlated with decreases in cortisol (Nakano, 2012).
PQQ enhances cognitive performance and short-term memory. It may assist the brain in staving off memory loss and cognitive deterioration as a result of aging and neurodegenerative diseases. Also, by virtue of its regenerating damaged brain and nerve cells property, PQQ supplements for neuropathy is purported to aid recovery from stroke and cerebral infarction as well.
Because of these and many other beneficial effects of PQQ on the mitochondria, nervescells, and the heart—the result is improved blood flow and heart function which encourages energy generation in the heart and offers superior antioxidant protection. Research shows that pqq also supports regeneration after heart attacks and reduces infarct magnitude.
PQQ helps the liver to metabolize fats so that it can break down more fat and turn it into more energy. Clinical data also suggest that it can reverse acute and chronic liver damage including that due to fatty liver disease.
PQQ not only supports your vital organs, but can also enhance and maintain increased levels of energy production at the cell level. It is an ideal sports supplement for athletes looking for natural products to improve performance.
Perhaps the most unpredictable benefit of PQQ use in cosmetic applications. It revitalizes your skin cells and reconstructs tissue for thicker skin, while diminishing wrinkles and skin pigmentation. PQQ is useful for anti-aging prevention for not only your brain, heart and liver, but also as a cosmetic anti-aging treatment for your skin.
Leading Chemical is a high-tech enterprise specializing in the R&D, production and sales of new food ingredients, functional food ingredients and natural plant active ingredients. The company is committed to offering healthy and safe raw materials for dietary supplements to global consumers. The produced PQQ is content and purity over 99%, more active materials and better effects after absorbed by the body, and has got various certificates. Any needs feel free to reach out to us.
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